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Hi this is Dr Russo, and you've probably heard that the environment one grows up and has a strong influence on their immune system and the potential for autoimmunity well published was a paper was recently published excuse me that looked at a group of children and tracked them from birth all the way through teenage years and tried to see if there was a correlation between the diversity of plant life around which where they grew up and any kind of topic condition to the skin like skin out immunity eczema psoriasis things like that and very interestingly they found that the more diverse and specifically the more wild the plant life was around ones home when growing up had a direct impact on autoimmunity but essentially what these authors showed was that the increased plant diversity specifically wild-type plants so not plants that you just bought at a store and implant it, but wild vegetation had a correlation with increased bacterial diversity on the skin that caused immunomodulator or increase in anti-inflammatory compounds in the blood and that than caused decrease in skin a topic conditions so as we continue to learn more and more about this field were learning that an increasingly more sterile environment will cause malfunctions in the immune system and here we see a nice illustration of that where we see when you have a very wild type environment that fosters high level of bacterial diversity and the skin in this case that causes release of anti-inflammatory compounds that has an immune modulator or immune balancing effect that than decreases a topic condition to the skin so a very, very interesting study here again I'll put up the cover slide here with a few notes that you may want to read through if you want a little more detail that you're seeing here and then the second slide is a slide from the study essentially just showing what we just went over which is kind of this cascade of some of these events so take here again is a little dirtier or a little more diverse of an environment seems to be protective against autoimmunity of multiple forms and in this case we see evidence for that of skin autoimmunity this is Dr Russo and I hope you find this helpful thanks
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